简介：journal of biological chemistry rss feed -- current issue

原站：http://www.jbc.org

“Journal of Biological Chemistry current issue”的内容更新

累计：8163 篇（自 2008-12-24 起）

更新：约7篇/天，更新比较频繁，最后更新1 天前

Journal of Biological Chemistry current issue

Ets2 in T-cell Development, Survival, and Apoptosis

interference of ras signaling deregulates thymocyte development in mouse models. however, the role of ets-2, a transcription factor that is phosphorylated on a critical threonine residue (thr-72) by the ras/mapk pathway in thymocyte development, has not been defined. transgenic mice overexpressing a phosphomutant ets-2 (t72a) in the thymus displayed redu... (1 天前)

http://inezha.com/w/7mp5k088n

Journal of Biological Chemistry current issue

Novel Essential pgants in Drosophila [Glycobiology a

mucin-type o-glycosylation represents a major form of post-translational modification that is conserved across most eukaryotic species. this type of glycosylation is initiated by a family of enzymes (galnac-ts in mammals and pgants in drosophila) whose members are expressed in distinct spatial and temporal patterns during development. previous work from ... (1 天前)

http://inezha.com/w/s4fu4088a

Journal of Biological Chemistry current issue

SIDT1 Mediates Contact-dependent Small RNA Transfer

locally initiated rna interference (rnai) has the potential for spatial propagation, inducing posttranscriptional gene silencing in distant cells. in caenorhabditis elegans, systemic rnai requires a phylogenetically conserved transmembrane channel, sid-1. here, we show that a human sid-1 orthologue, sidt1, facilitates rapid, contact-dependent, bidirectio... (1 天前)

http://inezha.com/w/wy4nv088b

Journal of Biological Chemistry current issue

Interphasic Regulation of VRK1 by MacroH2A1 [Signal

vrk1-mediated phosphorylation of histone h3 should be restricted in mitosis for consistent cell cycling, and defects in this process trigger cellular catastrophe. however, an interphasic regulator against vrk1 has not been actually investigated so far. here, we show that the histone variant macrodomain-containing histone h2a1.2 functions as a suppressor ... (1 天前)

http://inezha.com/w/lopop088z

Journal of Biological Chemistry current issue

Axonal Gradient of Arachidonic Acid-Phosphatidylchol

phosphatidylcholine (pc) is the most abundant component of lipid bilayers and exists in various molecular forms, through combinations of two acylated fatty acids. arachidonic acid (aa)-containing pc (aa-pc) can be a source of aa, which is a crucial mediator of synaptic transmission and intracellular signaling. however, the distribution of aa-pc within ne... (1 天前)

http://inezha.com/w/knflsk888

Journal of Biological Chemistry current issue

AMP Is an Adenosine A1 Receptor Agonist [Neurobiolog

numerous receptors for atp, adp, and adenosine exist; however, it is currently unknown whether a receptor for the related nucleotide adenosine 5′-monophosphate (amp) exists. using a novel cell-based assay to visualize adenosine receptor activation in real time, we found that amp and a non-hydrolyzable amp analog (deoxyadenosine 5′-monophosphonate, acp)... (1 天前)

http://inezha.com/w/du44fk88e

Journal of Biological Chemistry current issue

TA Modules of M. smegmatis [Metabolism]

the role of chromosomal toxin-antitoxin (ta) modules in bacterial physiology remains enigmatic despite their abundance in the genomes of many bacteria. mycobacterium smegmatis contains three putative ta systems, vapbc, mazef, and phd/doc, and previous work from our group has shown vapbc to be a bona fide ta system. in this study, we show that mazef and p... (1 天前)

http://inezha.com/w/ixpmkk88j

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