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简介:The latest research articles published by BMC Cell Biology
原站:http://www.biomedcentral.com/bmccellbiol/
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累计:265 篇(自 2008-12-24 起)
更新:约2篇/周,最后更新11 天前
BMC Cell Biology - Latest Articles
background:as many invertebrate species have multipotent cells that undergo cell growth and differentiation during regeneration and budding, many unique and interesting homeostatic factors are expected to exist in those animals. however, our understanding of such factors and global mechanisms remains very poor. single zooids of the tunicate, polyandroca... (11 天前)
BMC Cell Biology - Latest Articles
background:erlins are highly conserved proteins associated with lipid rafts within the endoplasmic reticulum (er). biochemical studies in mammalian cell lines have shown that erlins are required for er associated protein degradation (erad) of activated inositol-1,4,5-trisphosphate receptors (ip3rs), implying that erlin proteins might negatively regulate... (16 天前)
BMC Cell Biology - Latest Articles
background:sm22 has long been studied as an actin-associated protein. interestingly, levels of sm22 are often reduced in tumour cell lines, while they are increased during senescence possibly indicating a role for sm22 in cell fate decisions via its interaction with actin. in this study we aimed to determine whether reducing levels of sm22 could activel... (25 天前)
BMC Cell Biology - Latest Articles
background:a characteristic feature of frog reproduction is external fertilization accomplished outside the female's body. mature fertilization-competent frog eggs are arrested at the meiotic metaphase ii with high activity of the key meiotic regulators, maturation promoting factor (mpf) and cytostatic factor (csf), awaiting fertilization. if the eggs a... (50 天前)
BMC Cell Biology - Latest Articles
background:the human homologue of the drosophila discs-large tumor suppressor protein, hdlg, is a multi-domain cytoplasmic protein that localizes to the membrane at intercellular junction sites. at both synaptic junctions and epithelia cell-cell junctions, hdlg is known to recruit several signaling proteins into macromolecular complexes. hdlg is also fo... (55 天前)
BMC Cell Biology - Latest Articles
background:transforming growth factor-beta 1 (tgf-beta1) has been implicated in hyperoxia-induced cell death and impaired alveolarization in the developing lung. in addition, the c-junnh2-terminal kinase (jnk) pathway has been shown to have a role for tgf-beta1-mediated effects. we hypothesized that the jnk pathway is an important regulator of hyperoxia... (60 天前)
BMC Cell Biology - Latest Articles
background:embryonic stem cells (escs) can proliferate endlessly and are able to differentiate into all cell lineages that make up the adult organism. under particular in vitro culture conditions, escs can be expanded and induced to differentiate into cardiomyocytes in stirred suspension bioreactors (ssbs). however, in using these systems we must be cog... (61 天前)
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