RSS Molecular & Cellular Proteomics current issue
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简介:molecular & cellular proteomics rss feed -- current issue
原站:http://www.mcponline.org
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“Molecular & Cellular Proteomics current issue”的内容更新
累计:489 篇(自 2008-12-24 起)
更新:约3篇/周,最后更新12 天前
Molecular & Cellular Proteomics current issue
ankylosing spondylitis (as) is a common, inflammatory rheumatic disease that primarily affects the axial skeleton and is associated with sacroiliitis, uveitis, and enthesitis. unlike other autoimmune rheumatic diseases, such as rheumatoid arthritis or systemic lupus erythematosus, autoantibodies have not yet been reported to be a feature of as. we there... (12 天前)
Molecular & Cellular Proteomics current issue
affinity purification (ap) of protein complexes combined with lc-ms/ms analysis is the current method of choice for identification of protein-protein interactions. their interpretation with respect to significance, specificity, and selectivity requires quantification methods coping with enrichment factors of more than 1000-fold, variable amounts of tota... (12 天前)
Molecular & Cellular Proteomics current issue
development of new biomarkers needs to be significantly accelerated to improve diagnostic, prognostic, and toxicity monitoring as well as therapeutic follow-up. biomarker evaluation is the main bottleneck in this development process. selected reaction monitoring (srm) combined with stable isotope dilution has emerged as a promising option to speed this ... (12 天前)
Molecular & Cellular Proteomics current issue
knowledge of protein structures and protein-protein interactions is essential for understanding biological processes. chemical cross-linking combined with mass spectrometry is an attractive approach for studying protein-protein interactions and protein structure, but to date its use has been limited largely by low yields of informative cross-links (beca... (12 天前)
Molecular & Cellular Proteomics current issue
lung cancer is the leading cause of cancer-related death in the world. to explore tumor biomarkers for clinical application, two-dimensional fluorescence difference gel electrophoresis and subsequent maldi-tof/tof mass spectrometry were performed to identify proteins differentially expressed in 12 pairs of lung squamous cell tumors and their correspondi... (12 天前)
Molecular & Cellular Proteomics current issue
cyp3a4, an integral endoplasmic reticulum (er)-anchored protein, is the major human liver cytochrome p450 enzyme responsible for the disposition of over 50% of clinically relevant drugs. alterations of its protein turnover can influence drug metabolism, drug-drug interactions, and the bioavailability of chemotherapeutic drugs. such cyp3a4 turnover occur... (12 天前)
Molecular & Cellular Proteomics current issue
apoptosis is the most commonly described form of programmed cell death, and dysfunction is implicated in a large number of human diseases. many quantitative proteome analyses of apoptosis have been performed to gain insight in proteins involved in the process. this resulted in large and complex data sets that are difficult to evaluate. therefore, we dev... (12 天前)
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