简介：bioinformatics - rss feed of current issue

原站：http://bioinformatics.oxfordjournals.org

指数：

“Bioinformatics - current issue”的内容更新

累计：2176 篇（自 2008-12-24 起）

更新：约2篇/天，最后更新3 天前

Bioinformatics - current issue

The role of miRNAs in complex formation and control

summary: microribonucleic acid (mirnas) are small regulatory molecules that act by mrna degradation or via translational repression. although many mirnas are ubiquitously expressed, a small subset have differential expression patterns that may give rise to tissue-specific complexes.motivation: this work studies gene targeting patterns amongst mirnas wi... (3 天前)

http://inezha.com/w/4d5wz8la

Bioinformatics - current issue

Identifying small interfering RNA loci from high-thr

motivation: small interfering rnas (sirnas) are produced from much longer sequences of double-stranded rna precursors through cleavage by dicer or a dicer-like protein. these small rnas play a key role in genetic and epigenetic regulation; however, a full understanding of the mechanisms by which they operate depends on the characterization of the precur... (3 天前)

http://inezha.com/w/cf1xn8lq

Bioinformatics - current issue

Artemis: an integrated platform for visualization an

motivation: high-throughput sequencing (hts) technologies have made low-cost sequencing of large numbers of samples commonplace. an explosion in the type, not just number, of sequencing experiments has also taken place including genome re-sequencing, population-scale variation detection, whole transcriptome sequencing and genome-wide analysis of protein... (3 天前)

http://inezha.com/w/176u88ly

Bioinformatics - current issue

Read count approach for DNA copy number variants det

motivation: the advent of high-throughput sequencing technologies is revolutionizing our ability in discovering and genotyping dna copy number variants (cnvs). read count-based approaches are able to detect cnv regions with an unprecedented resolution. although this computational strategy has been recently introduced in literature, much work has been al... (3 天前)

http://inezha.com/w/pq5ntpl8

Bioinformatics - current issue

PASSion: a pattern growth algorithm-based pipeline f

motivation: rna-seq is a powerful technology for the study of transcriptome profiles that uses deep-sequencing technologies. moreover, it may be used for cellular phenotyping and help establishing the etiology of diseases characterized by abnormal splicing patterns. in rna-seq, the exact nature of splicing events is buried in the reads that span exon&nd... (3 天前)

http://inezha.com/w/3013hpld

Bioinformatics - current issue

MotEvo: integrated Bayesian probabilistic methods fo

motivation: probabilistic approaches for inferring transcription factor binding sites (tfbss) and regulatory motifs from dna sequences have been developed for over two decades. previous work has shown that prediction accuracy can be significantly improved by incorporating features such as the competition of multiple transcription factors (tfs) for bindi... (3 天前)

http://inezha.com/w/6j6l0pl6

Bioinformatics - current issue

Measuring the distance between multiple sequence ali

motivation: multiple sequence alignment (msa) is a core method in bioinformatics. the accuracy of such alignments may influence the success of downstream analyses such as phylogenetic inference, protein structure prediction, and functional prediction. the importance of msa has lead to the proliferation of msa methods, with different objective functions ... (3 天前)

http://inezha.com/w/f954zplv

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