RSS PNAS - RSS feed of Early Edition articles
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简介:proceedings of the national academy of sciences rss feed -- early edition
原站:http://www.pnas.org
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累计:10010 篇(自 2008-12-24 起)
更新:约9篇/天,更新比较频繁,最后更新10 小时前
PNAS - RSS feed of Early Edition articles
diabetes is a pathological condition characterized by relative insulin deficiency, persistent hyperglycemia, and, consequently, diffuse micro- and macrovascular disease. one therapeutic strategy is to amplify insulin-secretion capacity by increasing the number of the insulin-producing β cells without triggering a generalized proliferative response. here... (10 小时前)
PNAS - RSS feed of Early Edition articles
immature thymocytes expressing autoreactive t-cell receptors (tcr) can adopt differing cell fates: clonal deletion by apoptosis or deviation into alternative lineages such as foxp3+ regulatory t cells (treg). we revisited the role of the transcription factor nr4a1 (nur77), an immediate-early response gene induced by tcr engagement. nr4a1ko mice show clea... (10 小时前)
PNAS - RSS feed of Early Edition articles
insulin-like growth factor-binding protein 2 (igfbp2) is increasingly recognized as a glioma oncogene, emerging as a target for therapeutic intervention. in this study, we used an integrative approach to characterizing the igfbp2 network, combining transcriptional profiling of human glioma with validation in glial cells and the replication-competent aslv... (10 小时前)
PNAS - RSS feed of Early Edition articles
a common challenge in pathogen discovery by deep sequencing approaches is to recognize viral or subviral pathogens in samples of diseased tissue that share no significant homology with a known pathogen. here we report a homology-independent approach for discovering viroids, a distinct class of free circular rna subviral pathogens that encode no protein a... (10 小时前)
PNAS - RSS feed of Early Edition articles
climate change is a major environmental stress threatening biodiversity and human civilization. the best hope to secure staple food for humans and animal feed by future crop improvement depends on wild progenitors. we examined 10 wild emmer wheat (triticum dicoccoides koern.) populations and 10 wild barley (hordeum spontaneum k. koch) populations in isra... (1 天前)
PNAS - RSS feed of Early Edition articles
the cytochrome c oxidase cox2 has been purified from native membranes of the hyperthermophilic eubacterium aquifex aeolicus. it is a cytochrome ba3 oxidase belonging to the family b of the heme-copper containing terminal oxidases. it consists of three subunits, subunit i (coxa2, 63.9?kda), subunit ii (coxb2, 16.8?kda), and an additional subunit iia of 5.... (1 天前)
PNAS - RSS feed of Early Edition articles
many plants monitor day-length changes throughout the year and use the information to precisely regulate the timing of seasonal flowering for maximum reproductive success. in arabidopsis thaliana, transcriptional regulation of the constans (co) gene and posttranslational regulation of co protein are crucial mechanisms for proper day-length measurement in... (1 天前)
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