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Genome Biology - Latest Articles

简介：The latest research articles published by Genome Biology

原站：http://genomebiology.com/

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“Genome Biology - Latest Articles”的内容更新

累计：633 篇（自 2008-12-24 起）

更新：约4篇/周，最后更新9 天前

Genome Biology - Latest Articles

Predicting the effects of frameshifting indels

each human has approximately 50-280 frameshifting indels, yet their implications are unknown. we created sift indel, a prediction method for frameshifting indels which has 84% accuracy. the percentage of human frameshifting indels predicted to be gene-damaging is negatively correlated with allele frequency. we also show that although the first frameshift... (9 天前)

http://inezha.com/w/v0f9viwi

Genome Biology - Latest Articles

Population-specificity of human DNA methylation

background:ethnic differences in human dna methylation have been shown for a number of cpg sites, but the genome-wide patterns and extent of these differences are largely unknown. in addition, whether the genetic control of polymorphic dna methylation is population-specific has not been investigated.results:here we measure dna methylation near the tra... (9 天前)

http://inezha.com/w/mj4jpiwf

Genome Biology - Latest Articles

Sequencing three crocodilian genomes to illuminate t

the international crocodilian genomes working group (icgwg) will sequence and assemble the american alligator (alligator mississippiensis), saltwater crocodile (crocodylus porosus) and indian gharial (gavialis gangeticus) genomes. the status of these projects and our planned analyses are described.... (18 天前)

http://inezha.com/w/79p0sgwz

Genome Biology - Latest Articles

Dissecting the regulatory architecture of gene expre

background:expression quantitative trait loci (eqtls) are likely to play an important role in the genetics of complex traits; however their functional basis remains poorly understood. using the hapmap lymphoblastoid cell lines, we combine 1000 genomes genotypes and an extensive catalogue of human functional elements to investigate the biological mechani... (18 天前)

http://inezha.com/w/szfcfgww

Genome Biology - Latest Articles

MetaMerge: scaling up genome-scale metabolic reconst

reconstructed models of metabolic networks are widely used for studying metabolism in various organisms. many different reconstructions of the same organism often exist concurrently, forcing researchers to choose one of them at the exclusion of the others. we describe metamerge, an algorithm for semi-automatically reconciling a pair of existing metabolic... (18 天前)

http://inezha.com/w/w447kgw2

Genome Biology - Latest Articles

Uberon, an integrative multi-species anatomy ontolog

we present uberon, an integrated cross-species ontology consisting of over 6500 classes representing a variety of anatomical entities, organized according to traditional anatomical classification criteria. the ontology represents structures in a species-neutral way and includes extensive associations to existing species-centric anatomical ontologies, all... (18 天前)

http://inezha.com/w/llpf4gw0

Genome Biology - Latest Articles

SpliceGrapher: Detecting patterns of alternative spl

we propose a method for predicting splice graphs that enhances curated gene models using evidence from rna-seq and est alignments. results obtained using rna-seq experiments in arabidopsis thaliana show that predictions made by our splicegrapher method are more consistent with current gene models than predictions made by tau and cufflinks. furthermore, a... (18 天前)

http://inezha.com/w/k3fhvgw3

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Nature Biotechnology - Issue - nature.com science feeds

Nature Biotechnology journal featuring biotechnology articles and science research papers of commercial interest in pharmaceutical, medical, and environmental sciences.

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Nature Digest

nature digest is a monthly journal comprised of editorial, news feature, and special report, all of which appeared in the nature journal and news@nature.com and carefully selected by the japanese editor of the publication. nature digest also contains original articles on break-through research findings as well as interviews with leading japanese scientists. the "english with nature" section provides a set of tools to help japanese readers comprehend articles in nature.

指数 | 3人订阅